Death Lines

Cell death induction by Streptococcus pyogenes in four types of malignant cell lines

  Abstract   Background: The interest in using bacteria as anti- cancer therapeutic agents dates back to the end of the19th century. Some bacteria like Salmonella and Listeria replicate effectively inside malignant cell lines and suppress their growth. The bacterium Streptococcus pyogenes has become medically famous as a flesh-eating pathogen since mid-1980s. It is the causative agent of a life...

A lifetime in 20 lines : representation of death in

This paper investigates, in the context of biographical narratives in Literary Journalism, the Brazilian newspaper Folha de S.Paulo obituary section. The research corpus consists of 62 obituaries published since its implementation on October 30, 2007 to December 31 of the same year. Based on the biographical profile of the dead, this analysis seeks to understand coverage about the death from th...

Destabilization of Akt Promotes the Death of Myeloma Cell Lines

Constitutive activation of Akt is believed to be an oncogenic signal in multiple myeloma and is associated with poor patient prognosis and resistance to available treatment. The stability of Akt proteins is regulated by phosphorylating the highly conserved turn motif (TM) of these proteins and the chaperone protein HSP90. In this study we investigate the antitumor effects of inhibiting mTORC2 p...

Chemotherapeutic Candidate Inducing Immunological Death of Human Tumor Cell Lines

The immunological death induction by EY-6 on the human tumor cell lines was screened. Human colon carcinoma (HCT15, HCT116), gastric carcinoma (MKN74, SNU668), and myeloma (KMS20, KMS26, KMS34) cells were died by EY-6 treatment with dose-dependent manner. CRT expression, a typical marker for the immunological death, was increased on the EY-6-treated colorectal and gastric cancer cells. Interest...

silibinin mode of death in hepg2, and hela carcinoma cell lines